ichor.bio
链接:https://www.ichor.bio/about/
ichorbio总部位于牛津,致力于开发最高质量的试剂,成为研究级生物仿制药和体内抗体的最大供应商,推动科学研究的进步。ichorbio目前可提供140多种价格j具竞争力的体内研究抗体及相关同型对照抗体。同时,新增免疫检查点分子相关产品、科研用生物仿制药单克隆抗体、HLA-DR抗体、HLA-DQ抗体、体内抗体标记试剂盒,涵盖癌症研究、心血管研究、细胞生物学、表观遗传学和核信号、免疫学、微生物学、神经科学、信号转导和干细胞研究等各个研究领域,以满足科学探索的各种需求。
癌症 Cancer | 心血管 Cardiovascular | 细胞生物学 Cell Biology |
免疫学 Immunology | 微生物学 Microbiology | 神经科学 Neuroscience |
信号转导 Transduction | 标签和细胞标志物 Tags & Cell Markers | 干细胞 Stem Cells |
使用ichorbio产品发表的部分文献:
发表年份 | 文章标题 | 期刊名称 | 作者 | 引用的ichorbio产品 |
2023 | Synthetic immune checkpoint engagers protect HLA-deficient iPSCs and derivatives from innate immune cell cytotoxicity. | Cell Stem Cell | Gravina et al. | ICH4002 |
2023 | Blinatumomab Redirects Donor Lymphocytes against CD19+ Acute Lymphoblastic Leukemia without Relevant Bystander Alloreactivity after Haploidentical Hematopoietic Stem Cell Transplantation. | Int. J. Mol. Sci. | Mancusi et al. | ICH5025 |
2023 | A highly potent anti-VISTA antibody KVA12123 - a new immune checkpoint inhibitor and a promising therapy against poorly immunogenic tumors | Front Immunol. | Iadonato et al. | ICH4002 |
2023 | One-carbon unit supplementation fuels tumor-infiltrating T cells and augments checkpoint blockade | bioRxiv | Xu et al. | IHC1132 |
2023 | A CRISPR activation screen identifies MUC-21 as critical for resistance to NK and T cell-mediated cytotoxicity | Journal of Experimental & Clinical Cancer Research | Lee et al. | ICH5015 |
2023 | Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) neutralization counteracts T cell immune evasion in breast cancer | Journal for ImmunoTheraphy of Cancer | Travelli et al. | ICH2248 |
2023 | M0bile Affinity Selection Chromatography Analysis of Therapeutic Monoclonal Antibodies | Analytical Chemistry | Narsimhan et al. | ICH4011, ICH4009, ICH4019 |
2023 | Injectable hydrogel loaded with lysed OK-432 and doxorubicin for residual liver cancer after incomplete radiofrequency ablation | Journal of Nanobiotechnology | Cao et al. | ICH1077, ICH1042, and ICH1043 |
2023 | Aconite aqueous extract inhibits the growth of hepatocellular carcinoma through CCL2-dependent enhancement of natural killer cell infiltration | Journal of Integrative Medicine | Yang et al. | ICH1128UL |
2023 | WNT4 promotes macrophage polarization via granulosa cell M-CSF and reduces granulosa cell apoptosis in endometriosis | Cytokine | Yuan et al. | ICH1026 |
FAQ
1.低内毒素和超低内毒素有什么区别?
答:ichorbio生产两种用于体内使用的格式:低内毒素和超低内毒素。超低格式具有更高的纯度,更低的内毒素,更低的聚集,并且经过了与将要使用的动物相关的病原体测试。
2.抗体如何储存?效期多久?
答:遵循我们数据表上列出的存储信息。只有在存储温度正确时才保证一年的使用效期。
3.抗体溶液中发现有沉淀物是什么?
答:环境条件,如温度变化、冻结/解冻、运输过程中的摇晃以及长期存储可能导致抗体溶液出现沉淀或絮块。絮块通常是缓冲盐从溶液中沉淀出来或者一小部分蛋白质聚集。如果轻轻地反复倒置小瓶,应该可以去除沉淀。如果不能去除,我们建议通过过滤或离心来去除絮块。
对于过滤,建议使用无菌的0.2μM过滤器。对于离心,我们建议将抗体溶液转移到无菌离心管中(不要在提供的冷冻瓶中离心),并在10k rpm下离心5分钟。更建议使用过滤而不是离心,因为离心可能使样品发热的时间比过滤的方式长,而过滤则可以非常快速地完成。无论选择哪种方法,都应使用无菌过滤器、注射器、管子等,并在生物安全柜中操作,以确保溶液保持无菌。此外,使用这些方法可以去除沉淀而不会有显著的蛋白质损失。如果在离心或过滤后担心损失,您可以检查离心或过滤后的蛋白质浓度,并将其与提供的CoA上的浓度进行比较。
4.稀释抗体的最佳方法是什么?
答:可以使用与抗体配方w全相符的无菌1*PBS。在稀释时,建议使用冷缓冲液,并通过在生物安全柜中操作以及使用无菌移液管头、管子、注射器和缓冲液来保持无菌。应避免将抗体稀释到工作浓度并在4℃以上存储超过一天。
更多其它产品详情请查询ichorbio网站或咨询ichorbio中国代理上海起发。
下图为ichorbio公司授权上海起发作为中国区域代理的授权书。
ichorbio热卖产品
货号 | 产品名称 | 规格 | 品牌 |
ICH1132-100mg | Anti-Mouse PD-1 In Vivo Antibody – Low Endotoxin (RMP1-14) | 100mg | ichorbio |
ICH5025-1mg | Blinatumomab Biosimilar - Research Grade [ICH5025] | 1mg | ichorbio |
ICH1132-50mg | Anti-Mouse PD-1 In Vivo Antibody - Low Endotoxin (RMP1-14) | 50mg | ichorbio |
ICH1114-5mg | Anti-Mouse RANKL In Vivo Antibody - Low Endotoxin (IK22/5) | 5mg | ichorbio |
ICH5056-20mg | Abciximab Biosimilar - Research Grade | 20mg | ichorbio |
ICH1009-25mg | Bulk anti-Human CD14 antibody (UCHM-1) | 25mg | ichorbio |
ICH2255-25mg | Bulk Human IgG2 Isotype Control (IB2) | 25mg | ichorbio |
ICH5025-5mg | Blinatumomab Biosimilar - Research Grade | 5mg | ichorbio |
ICH4002-1mg | Alemtuzumab Biosimilar - Research Grade | 1mg | ichorbio |
ICH1002-25mg | Bulk anti-Human CD3 antibody (UCHT-1) | 25mg | ichorbio |
ICH1002-5mg | Bulk anti-Human CD3 antibody (UCHT-1) | 5mg | ichorbio |
ICH2249UL-5mg | Mouse IgG3 Isotype Control for In Vivo - Ultra Low Endotoxin (MG3-35) [ICH2249UL] | 5mg | ichorbio |
ICH5056-1mg | Abciximab Biosimilar - Research Grade | 1mg | ichorbio |
ICH1086-5mg | Anti-Mouse PD-L1 In Vivo Antibody - Low Endotoxin (10F.9G2) | 5mg | ichorbio |
ICH1075-5mg | Anti-Mouse CD155 In Vivo Antibody – Low Endotoxin (4.24) | 5mg | ichorbio |
ICH1015-25mg | Bulk anti-Human CD56 antibody (ERIC-1) | 25mg | ichorbio |
ICH5025-0.5mg | Blinatumomab Biosimilar - Research Grade [ICH5025] | 0.5mg | ichorbio |
ICH2254-100mg | Bulk Human IgG1 Isotype Control (IB1) [ICH2254] | 100mg | ichorbio |
ICH1086-100mg | Anti-Mouse PD-L1 In Vivo Antibody - Low Endotoxin (10F.9G2) | 100mg | ichorbio |
ICH1002-50mg | Bulk anti-Human CD3 antibody (UCHT-1) | 50mg | ichorbio |
ICH1002-100mg | Bulk anti-Human CD3 antibody (UCHT-1) | 100mg | ichorbio |
ICH1025-5mg | Bulk anti-Human HLA-DQ antibody (1a3) | 5mg | ichorbio |
ICH1024-5mg | Bulk anti-Human HLA-DP antibody (B7/21) | 5mg | ichorbio |
ICH1183-100mg | Mouse anti-Mouse PD-L1 antibody (10F.9G2) [ICH1183] | 100mg | ichorbio |
ICH2254LALA-5mg | Human IgG1 Isotype Control (IB1) LALA | 5mg | ichorbio |
ICH5070-1mg | Enfortumab Biosimilar - Research Grade | 1mg | ichorbio |
ICH1042-1mg | Anti-Mouse CD4 In Vivo Antibody - Low Endotoxin (GK1.5) | 1mg | ichorbio |
ICH2250-5mg | Mouse IgG2b Isotype Control for In Vivo – Low Endotoxin (MPC-11) | 5mg | ichorbio |
ICH1130-25mg | Anti-Mouse, Human CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) | 25mg | ichorbio |
ICH1172-25mg | Bulk anti-Human CCR5 antibody (HEK/1/85a/7a) | 25mg | ichorbio |
ICH1028-25mg | Bulk anti-Human CD119 antibody (GIR 208) | 25mg | ichorbio |
ICH4014-0.1mg | Ado-trastuzumab emtansine Biosimilar - Research Grade | 0.1mg | ichorbio |
ICH1094-25mg | Anti-Mouse CD120a In Vivo Antibody - Low Endotoxin (55R-170) | 25mg | ichorbio |
ICH1117-25mg | Anti-Mouse IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147) | 25mg | ichorbio |
ICH1023-25mg | Bulk anti-Human MHC Class I antibody (W6/32) | 25mg | ichorbio |
ICH1007-25mg | Bulk anti-Human CD11b antibody (ICRF44) | 25mg | ichorbio |
ICH1114-25mg | Anti-Mouse RANKL In Vivo Antibody - Low Endotoxin (IK22/5) | 25mg | ichorbio |
ICH1011-25mg | Bulk anti-Human CD19 antibody (SJ25-C1) | 25mg | ichorbio |
ICH1040-25mg | Anti-Mouse CD3e In Vivo Antibody - Low Endotoxin (500A2) | 25mg | ichorbio |
ICH1032-25mg | Bulk anti-Human iNKT cell antibody (6B11) | 25mg | ichorbio |
ICH1196-25mg | Anti-Mouse CD134 In Vivo Antibody (OX-86) - Low Endotoxin | 25mg | ichorbio |
ICH1092-25mg | Anti-Mouse Dendritic Cells In Vivo Antibody - Low Endotoxin (33D1) | 25mg | ichorbio |
ICH1122-25mg | Anti-Mouse IFNAR1 In Vivo Antibody - Low Endotoxin (MAR1-5A3) | 25mg | ichorbio |
ICH1021-25mg | Bulk anti-Human EGFR antibody (EGFR.1) | 25mg | ichorbio |
ICH1206-25mg | Anti-Mouse IL-21R In Vivo Antibody (4A9) - Low Endotoxin | 25mg | ichorbio |
ICH2254-5mg | Bulk Human IgG1 Isotype Control (IB1) | 5mg | ichorbio |
ICH4005-20mg | Eculizumab Biosimilar - Research Grade | 20mg | ichorbio |
ICH1137-25mg | Anti-Mouse TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) | 25mg | ichorbio |
ICH1076-5mg | Anti-Mouse CD172a In Vivo Antibody - Low Endotoxin (P84) | 5mg | ichorbio |
ICH5025-0.1mg | Blinatumomab Biosimilar - Research Grade | 0.1mg | ichorbio |
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